Eric Dane: Grey's Anatomy's Dr. McSteamy and Euphoria Star Dies at 53

Eric Dane was an American actor best known as the charming plastic surgeon Dr. Mark Sloan, nicknamed "McSteamy," on Grey's Anatomy. Born on November 9, 1972, in San Francisco, California, Dane began acting after a high school production of Arthur Miller's All My Sons and built a career that spanned more than three decades.

Dane joined Grey's Anatomy in 2005 and became a series regular in its third season. He played Multiple Man in X-Men: The Last Stand (2006), starred as Captain Tom Chandler in TNT's The Last Ship from 2014 to 2018, and played Cal Jacobs in HBO's Euphoria from 2019 until his death.

Dane married actress Rebecca Gayheart in 2004, and they had two daughters. He had spoken publicly about his diagnosis with amyotrophic lateral sclerosis (ALS), and he died of respiratory failure related to the disease in Los Angeles on February 19, 2026, at age 53. Remembered for his charisma and his courage in sharing his illness, he leaves a body of work that will continue to entertain.

Achievements: Played Dr. Mark Sloan on Grey's Anatomy (2005-2012), appeared as Multiple Man in X-Men: The Last Stand (2006), starred in The Last Ship (2014-2018), played Cal Jacobs in Euphoria (2019-2026).

Birth: November 9, 1972 - San Francisco, California.

Profession: Actor.

Interesting Facts: Dane was raised in his mother's Jewish faith and had a bar mitzvah. He also played varsity water polo in high school before turning to acting.